Stem Cell Reviews and Reports (SCRR) covers contemporary and emerging areas in stem cells by publication of reviews, original data reports (full reports and short reports), protocols, novel hypotheses and commentaries. The scope related to stem cells is broad and includes topics in stem cell biology covering basic, clinical, biotechnology, regulatory, and ethical aspects of embryonic and adult stem cells, induced pluripotent stem cells, fate choice, specific lineage and cloning issues, translational studies, and diseases where stem cell anomalies play a key role and related matters. Original articles are expected to provide novel insights based on new data. Reviews, commentaries and hypotheses should provide syntheses of current concepts in the field and discuss emerging issues and controversies; the nature of the topic or idea being discussed will dictate appropriate choice of article type. Protocols will help accelerate studies in the field, by providing practical and step by step descriptions of established or emerging protocols and techniques of utility for both established and novice investigator.